Stem cells are able to differentiate into various cell types, release growth factors, organize wound healing, modulate the inflammatory response and exhibit immunomodulatory effects
Muscle derived mesenchymal stem cells produced by Revatis technology are truly pluripotent. Numerous lines have already been obtained such as osteocytes, chondrocytes, tenocytes, keratinocytes, endothelial, nerve, muscle and cardiac cells as well as hepatic or pancreatic progenitors. Pluripotency is fundamental for personalized organ-on-chip development and tissue engineering.
Stem cells are able to release a multitude of substances into the extracellular environment in order to organize optimal healing. These include microRNAs, growth factors, mainly anti-inflammatory cytokines as well as anti-infectious and immunomodulatory agents. Modulation of neutrophil activation by stem cells recently been demonstrated and opens up therapeutic perspectives in severe pathological conditions such as systemic inflammatory syndrome (SIRS), acute respiratory distress syndrome (ARDS) and multiple organ failure (MOF)
During this interaction, a transfer of stem cells mitochondria to cells with mitochondrial dysfunction can occur under certain conditions. This property is fundamental and promising for future treatments of degenerative and metabolic pathologies.
Less invasive sampling facilitates autologous use and personalized medicine applications, both diagnostic and tissue engineering such as 3D bioprinting.
Cell production in aseptic isolator, quality management system and GMP certification ensure stable and high quality supply.
The team is very experienced in the differentiation, culture, production and quality control of stem cells as well as in the management of research projects.
Revatis shares patents, knowledge and know-how with its partners.
The recent work of the Revatis team enables us to offer our partners quality cells, differentiated or not. Whether for your developments in R&D or in the field of therapeutic medicine, Revatis is well positioned to become your partner of choice.
Our team will be happy to provide you with a tailor-made solution.