Revatis S.A. • Stem cells Stem cells are the essential components of cell therapy and regenerative medicine

Stem cells are able to differentiate into various cell types, release growth factors, organize wound healing, modulate the inflammatory response and exhibit immunomodulatory effects

Cell differentiation and pluripotency

Muscle derived mesenchymal stem cells produced by Revatis technology are truly pluripotent. Numerous lines have already been obtained such as osteocytes, chondrocytes, tenocytes, keratinocytes, endothelial, nerve, muscle and cardiac cells as well as hepatic or pancreatic progenitors. Pluripotency is fundamental for personalized organ-on-chip development and tissue engineering.

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Cell differentiation and pluripotency

Paracrine effects

Stem cells are able to release a multitude of substances into the extracellular environment in order to organize optimal healing. These include microRNAs, growth factors, mainly anti-inflammatory cytokines as well as anti-infectious and immunomodulatory agents. Modulation of neutrophil activation by stem cells recently been demonstrated and opens up therapeutic perspectives in severe pathological conditions such as systemic inflammatory syndrome (SIRS), acute respiratory distress syndrome (ARDS) and multiple organ failure (MOF)

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Paracrine effects

Stem cell / deficient cell interaction

During this interaction, a transfer of stem cells mitochondria to cells with mitochondrial dysfunction can occur under certain conditions. This property is fundamental and promising for future treatments of degenerative and metabolic pathologies.

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Stem cell / deficient cell interaction

Revatis stem cells open up the possibilities

Perspectives in personalized medicine

Less invasive sampling facilitates autologous use and personalized medicine applications, both diagnostic and tissue engineering such as 3D bioprinting.

Perspectives in personalized medicine

Focus on the quality of production

Cell production in aseptic isolator, quality management system and GMP certification ensure stable and high quality supply.

Focus on the quality of production

High level scientific environment

The team is very experienced in the differentiation, culture, production and quality control of stem cells as well as in the management of research projects.

High level scientific environment

Strong intellectual property

Revatis shares patents, knowledge and know-how with its partners.

Strong intellectual property

Interested in working with Revatis stem cells?

The recent work of the Revatis team enables us to offer our partners quality cells, differentiated or not. Whether for your developments in R&D or in the field of therapeutic medicine, Revatis is well positioned to become your partner of choice.

Interested in a collaboration?

Interested in a collaboration?

Our team will be happy to provide you with a tailor-made solution.